The cross-sectional mouse cohort (6, 12, 18, and 24 months) includes more than 1,500 male and female SWISS mice (normal diet and high-fat, high-sucrose diet) for which an in-depth functional phenotyping (motor activity, cognition, cardiac function, urinary function, nutrition/vitality) has been carried out, as well as the collection of more than 50,000 biological samples (plasma and dry pellets, urine, faeces, brain, heart, adipose tissue, skeletal muscles, digestive tract, liver, skin and kidneys).