2025

The INSPIRE-T longitudinal observational study centred on intrinsic capacity: baseline data. Guyonnet S e al., J Gerontol A Biol Sci Med Sci. 2025 Aug 18

Acceleration and Functional Capacities Across the Lifespan in the INSPIRE-T Cohort. J Cachexia Sarcopenia Muscle. Sánchez-Sánchez JL et al., J Cachexia Sarcopenia Muscle. 2025 Aug 16

Physical activity and Alzheimer’s disease: a call for evidence incorporation. Sánchez-Sánchez JL, de Souto Barreto P., J Prev Alzheimers Dis. 2025 Aug 12

Associations of Skin Biomechanical Properties With Biological Aging Clocks and Longitudinal Changes in Intrinsic Capacity in Adults Aged 20-93: The INSPIRE-T Project. Lu WH et al., Aging Cell. 2025 Aug 10

Associations between intrinsic capacity, plasma p-tau181 and cognitive function over a 5-year follow-up among community-dwelling older adults: a secondary analysis of the MAPT Study. Giudici KV et al., J Frailty Aging. 2025 Aug

Cross-sectional associations of plasma vitamin D with plasma phosphorylated tau-181 and plasma neurofilament light chain in older adults with memory complaints. Hooper C et al., Neurobiol. 2025 Jul 22

A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors. Fuentealba M et al., Nat Aging. 2025 Jul 5

Reference centiles for intrinsic capacity to monitor clinical health outcomes in real-world primary care cohorts. de Souto Barreto P et al., Nat Aging. 2025 Jul 5

Identification of Functional Cellular Markers Related to Human Health, Frailty and Chronological Age. Brodeau C et al., Aging Cell. 2025 Jul 1

HealthAge: evaluation of intrinsic capacity changes in humans, mice, and killifish to explore the biology of aging. Guyonnet S, et al., Geroscience. 2025 Jun 16

Lifestyle factors and plasma biomarkers of Alzheimer’s disease: A narrative review. Hooper C et al., J Prev Alzheimers Dis. 2025 Jun 12

Mitochondrial Bioenergetic Profiling in T Cell Subsets Associates With Functional Health in Older Adults: A Cross-sectional Analysis From the INSPIRE-T Cohort. Jabrane-Ferrat N et al., J Gerontol A Biol Sci Med Sci. 2025 Jun 10

Pathogenicity of commensal gut biofilm in prefrail aging. NPJ Biofilms Microbiomes. Le Cosquer G et al., NPJ Biofilms Microbiomes. 2025 May 22

Cross-sectional associations of epigenetic clocks with intrinsic capacity and functional ability in older adults with frailty and cognitive impairment: the COGFRAIL study. Valenzuela PL et al., Geroscience. 2025 May 16

The associations between biological markers of aging and appetite loss across adulthood: retrospective case-control data from the INSPIRE-T study. Turesson A et al., Geroscience. 2025 May 10

The relationship between physical activity and appetite among older adults – A scoping review. Turesson A et al., J Nutr Health Aging. 2025 May

Hallmarks of aging and Alzheimer’s Disease pathogenesis: Paving the route for new therapeutic targets. Bellelli F et al., Ageing Res Rev. 2025 Apr

Cross-sectional and longitudinal associations between physical activity and intrinsic capacity in healthy older adults from the MAPT study. Raffin J et al., Arch Gerontol Geriatr. 2025 Mar

Implementing the WHO ICOPE Program in Clinical Practice: Three Years of Lessons From Monitoring 27 082 Participants Using the ICOPE Monitor Digital Tool. Berbon C et al., J Gerontol A Biol Sci Med Sci. 2025 Feb 10

Associations between moderate-to-vigorous physical activity, p-tau181, and cognition in healthy older adults with memory complaints: a secondary analysis from the MAPT. Raffin J et al., Lancet Healthy Longev. 2025 Feb 6

Body composition and aging: cross-sectional results from the INSPIRE study in people 20 to 93 years old. Briand M et al., Geroscience. 2025 Feb

Sex-specific associations of neurodegeneration and inflammatory biomarkers with intrinsic capacity in older adults: Findings from the 4-year longitudinal Multidomain Alzheimer’s Prevention Trial (MAPT). de Assunção Cortez Corrêa LC et al., Maturitas. 2025 Feb

Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR). Izquierdo M et al., J Nutr Health Aging. 2025 Jan 29

Nutritional specificity of frailty: from epidemiological and clinical evidence to potential mechanisms. Lengelé L et al., Curr Opin Clin Nutr Metab Care. 2025 Jan 1

Sarcopenia and the biological determinants of aging: A narrative review from a geroscience perspective. Nunes-Pinto M et al., Ageing Res Rev. 2025 Jan

2024

Self-Reported Fatigue and Its Cross-Sectional Associations with Physical Function throughout Adulthood: The INSPIRE-T Cohort. Matsumoto D et al., J Frailty Aging. 2024

Now and future: Strategies for diagnosis, prevention and therapies for Alzheimer’s disease. Shi J et al., Sci Bull. 2024 Sep 28

Real-life intrinsic capacity screening data from the ICOPE-Care program. de Souto Barreto P et al., Nat Aging. 2024 Sep 4

Mild behavioral impairment domains are longitudinally associated with pTAU and metabolic biomarkers in dementia-free older adults. Gonzalez-Bautista E et al., Alzheimers Dement. 2024 Jul 20

Association of intrinsic capacity with functional decline and mortality in older adults: a systematic review and meta-analysis of longitudinal studies. Sánchez-Sánchez JL et al., Lancet Healthy Longev. 2024 Jul 5

Predictive Capacity of the Integrated Care for Older People Screening Tool for Intrinsic Capacity Impairments: Results From the INSPIRE-T Cohort. Guidici KV et al., Gerontol A Biol Sci. 2024 Jul 1

Drugs for Alzheimer’s disease: Where are we coming from? Where are we going? Angioni D et al., Sci Bull 2024 May 30

Integrative multi metabolomics to early predict cognitive decline among amyloid positive community-dwelling older adults. Tremblay-Franco M et al., J Gerontol A Biol Sci Med Sci. 2024. May 1

Plasma p-tau181 as an outcome and predictor of multidomain intervention effects: a secondary analysis of a randomised, controlled, dementia prevention trial. Coley N et al., Lancet Healthy Longev. 2024 Feb 5

Dementia research in 2023: the year of anti-amyloid immunotherapy. Delrieu J et al., Lancet Neurol. 2024 Jan 23

 

2023

Reference centiles for intrinsic capacity throughout adulthood and their association with clinical outcomes: a cross-sectional analysis from the INSPIRE-T cohort. Lu WH et al., Nat Aging. 2023 Dec 3

Looking at frailty and intrinsic capacity through a geroscience lens: the ICFSR & Geroscience Task Force. de Souto Barreto P et al., Nat Aging. 2023 Dec 3