{"id":545,"date":"2020-04-24T14:17:59","date_gmt":"2020-04-24T12:17:59","guid":{"rendered":"https:\/\/inspire.chu-toulouse.fr\/human-cohorts\/"},"modified":"2024-04-19T15:37:50","modified_gmt":"2024-04-19T13:37:50","slug":"pillar4","status":"publish","type":"page","link":"https:\/\/ihuhealthage.fr\/fr\/pillar4\/","title":{"rendered":"Pillar 4: A Geroscience Trial Platform"},"content":{"rendered":"<h2 class=\"chapeau\" style=\"text-align: justify;\">Geroscience medicine of tomorrow directly targets the biology of aging.\u00a0 Aging is the major risk factor for functional decline and chronic age-related diseases.<\/h2>\n<p style=\"text-align: justify;\">As suggested by the Geroscience theory, by acting on the biological aging at the root of multiple-age related diseases (i.e. dementia, diabetes, cancer, heart disease) and functional decline, we can stay healthier and functionally active longer. In other words, preventive efforts that address biological aging are based on a systemic perspective rather than a single disease \u2013 where the biology of aging is an integral part of functional decline and multiple diseases, and prevention can be handled before the beginning of chronic diseases and disability.<\/p>\n<p style=\"text-align: justify;\">The IHU HealthAge will build an internationally connected framework and platform to connect clinical trials that test novel Geroscience drugs.\u00a0 This platform takes advantage of the established Toulouse expertise in running small to moderate to large-scale trials. Further, the platform builds on the international guideline leadership of the team on defining a core set of outcomes (test) variables to compare the effectiveness of the interventions on the biology of aging across trials. Additionally, the trial platform will include a trial biobank to validate novel biomarkers of aging in response to novel treatments and will in a pre-clinical platform test causality of the novel interventions in the established Toulouse INSPIRE animal models.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Geroscience medicine of tomorrow directly targets the biology of aging.\u00a0 Aging is the major risk factor for functional decline and chronic age-related diseases. As suggested by the Geroscience theory, by acting on the biological aging at the root of multiple-age related diseases (i.e. dementia, diabetes, cancer, heart disease) and functional decline, we can stay healthier [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-545","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pillar 4: A Geroscience Trial Platform - IHU Healthage<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ihuhealthage.fr\/fr\/pillar4\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pillar 4: A Geroscience Trial Platform - IHU Healthage\" \/>\n<meta property=\"og:description\" content=\"Geroscience medicine of tomorrow directly targets the biology of aging.\u00a0 Aging is the major risk factor for functional decline and chronic age-related diseases. As suggested by the Geroscience theory, by acting on the biological aging at the root of multiple-age related diseases (i.e. dementia, diabetes, cancer, heart disease) and functional decline, we can stay healthier [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ihuhealthage.fr\/fr\/pillar4\/\" \/>\n<meta property=\"og:site_name\" content=\"INSPIRE\" \/>\n<meta property=\"article:modified_time\" content=\"2024-04-19T13:37:50+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ihuhealthage.fr\/fr\/pillar4\/\",\"url\":\"https:\/\/ihuhealthage.fr\/fr\/pillar4\/\",\"name\":\"Pillar 4: A Geroscience Trial Platform - IHU Healthage\",\"isPartOf\":{\"@id\":\"https:\/\/ihuhealthage.fr\/fr\/#website\"},\"datePublished\":\"2020-04-24T12:17:59+00:00\",\"dateModified\":\"2024-04-19T13:37:50+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/ihuhealthage.fr\/fr\/pillar4\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/ihuhealthage.fr\/fr\/pillar4\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/ihuhealthage.fr\/fr\/pillar4\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/ihuhealthage.fr\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Pillar 4: A Geroscience Trial Platform\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/ihuhealthage.fr\/fr\/#website\",\"url\":\"https:\/\/ihuhealthage.fr\/fr\/\",\"name\":\"IHU Healthage\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/ihuhealthage.fr\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Pillar 4: A Geroscience Trial Platform - IHU Healthage","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ihuhealthage.fr\/fr\/pillar4\/","og_locale":"fr_FR","og_type":"article","og_title":"Pillar 4: A Geroscience Trial Platform - IHU Healthage","og_description":"Geroscience medicine of tomorrow directly targets the biology of aging.\u00a0 Aging is the major risk factor for functional decline and chronic age-related diseases. 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